Born on September 6, 1963 in Bucharest (Romania). Studies in Biology at the Technical University Munich (1982-1985) and in Molecular Biology at Princeton University (1985-1990); PhD with Jeff Stock on the mechanism of signal transduction in bacterial chemotaxis (1991). Postdoctoral fellow with Andreas Plückthun at the Gene Center of the University, Munich (1992-1993), working on antibody engineering. Research assistant with Wolfgang Baumeister at the Max-Planck-Institute for Biochemistry, Martinsried (1993-1997), working on the development and application of sequence analysis tools, and on the structure and function of the proteasome. Senior Computational Biologist, later Assistant Director of Bioinformatics, at SmithKline Beecham Pharmaceuticals, Collegeville, USA (1997-2001), working on the development of antibiotics. Since 2001, director of the Department of Protein Evolution at the Max-Planck-Institute for Biology, Tübingen.